| Description: | <p>The ISRE Reporter – HEK293 Cell Line is designed for monitoring the activity of the JAK/STAT signaling pathway. The ISRE Reporter – HEK293 Cell Line contains the firefly luciferase gene under the control of ISRE stably integrated into HEK29 |
|---|---|
| Synonym(s): | JAK reporter, STAT reporter, ISRE cell line |
| Supplied As: | Each vial contains ~1.5 X 106 cells in 1 ml of 10% DMSO. |
| Biological Activity: | This cell line is validated for the response to stimulation with interferon Alpha A and to treatment with JAK inhibitor. |
| Host Cell line: | HEK293 cells |
| Mycoplasma Testing: | The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma Aldrich) to confirm the absence of Mycoplasma species. |
| Format: | aqueous solution containing DMSO |
| Instructions for use: | See data sheet for detailed culturing and assay protocol. |
| Storage / Stability: | Store in liquid nitrogen immediately upon receipt. |
| Application(s): | • Monitor IFNα-induced activity and the JAK/STAT pathway activity. • Screen for activators or inhibitors of the JAK/STAT signaling pathway. |
| Notes: | Contact us for pricing. License Disclosure : Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. Publications using this cell line should reference West Bioscience, Inc., San Diego. |
| Warning(s): | Avoid freeze/thaw cycles |
| Scientific Category: | Recombinant Cell Lines(s) |
| Product Type: | Cell Signaling Pathway |