- Species:Human
- Host Species:E. coli
- MW:14.6 kDa
|
- Genbank #:NM_003528
- Tag(s):N-terminal His-tag
- a.a:2–126(end)
|
| Description: |
Human Histone 2B, GenBank Accession No. NM_003528, a.a. 2-126(end) with N-terminal His-tag, MW = 14.6 kDa, expressed in an <i>E. coli</i> expression system. |
| UniProt |
Q16778 |
| Synonym(s): |
H2B/c,H2BFC,HIST1H2BL,Histone H2B |
| Formulation: |
50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol, 1 mM PMSF and 1 mM DTT. |
| Format: |
Aqueous buffer solution |
| Storage / Stability: |
>6 months at |
| Application(s): |
Useful as a substrate for histone methyltransferase and acetyltransferase assays. Ideal for screening small molecular inhibitors of histone modifying enzymes for drug discovery and HTS applications. |
| Reference(s): |
1. Osley, M.A. Brief Funct. Genomic
Proteomic 5(3):179-89 (2006).
2. Wyrick, J.J. and Parra, M.A.. Biochim
Biophys Acta. 1789(1):37-44 (2009).
3. Emre, N.C. and Berger, S.L. Cold Spring
Harb Symp Quant Biol. 69: 289-99 (2004) |
| Warning(s): |
Avoid freeze/thaw cycles |
| Scientific Category: |
Methyltransferase(s) |
| Product Type: |
Substrates |
