- Species:Human
- Host Species:Sf9 insect cells
- MW:86 kDa (complex)
|
- Genbank #:NM_006892(DNMT3B), NM_013369 (DNMT3L)
- Tag(s):N-terminal His, N-terminal GST-tag
- a.a:564–853(end), DNMT3b; 160–387(end), DNMT3L
|
| Description: |
Complex of human DNA methyl-transferase 3B (DNMT3B), GenBank Accession No. NM_006892, a.a. 564-853(end) with N-terminal His-tag, MW=34 kDa, and DNMT3L (GenBank Accession No. NM_013369), a.a. 160-387(end), with an N-terminal GST-tag, MW = 52 kDa, co-expres |
| UniProt |
Q9UBC3 (DNMT3B), Q9UJW3 (DNMT3L) |
| Specific Activity: |
≥0.52 pmol/min/ |
| Assay Conditions: |
Assayed using West Bioscience DNMT3B Assay Kit, Cat. #52034. Add 50 |
| Formulation: |
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, and 20% glycerol |
| Format: |
aqueous buffer solution |
| Storage / Stability: |
>6 months at –80°C. |
| Application(s): |
Useful for the study of DNA methylation, screening inhibitors, and selectivity profiling. |
| Warning(s): |
Avoid freeze/thaw cycles. |
| Scientific Category: |
Methyltransferase(s) |
| Product Type: |
Enzymes |
