- Species:Human
- Host Species:Sf9 insect cells
- MW:89 kDa
|
- Genbank #:NM_004304
- Tag(s):N-terminal GST-tag
- a.a:1058–1620 (end)
|
| Description: |
Human anaplastic lymphoma receptor tyrosine kinase (ALK), also known as CD246 and NBLST3, (GenBank Accession No. NM_004304), a.a. 1058-1620 (end) with N-terminal GST-tag, MW = 89 kDa, expressed in a Baculovirus infected Sf9 cell expression system. |
| UniProt |
Q9UM73 |
| Synonym(s): |
ALK, CD246, anaplastic lymphoma receptor tyrosine kinase, NBLST3 |
| Specific Activity: |
77 pmol/min/ |
| Assay Conditions: |
Assay was done in a Kinase buffer using 0.2 mg/ml IGF1Rtide as a substrate with 20 |
| Formulation: |
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, and 20% glycerol. |
| Format: |
aqueous buffer solution |
| Storage / Stability: |
>6 months at -80°C. |
| Application(s): |
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Reference(s): |
1. Ren, H., et al., Cancer Res. 2012,72(13):3312-3323.
2. Zhu, S., et al., Cancer Cell 2012,21(3):362-373.
3. Schonherr, C., et al., Crit Rev Oncog. 2012,17(2):123-143 |
| Warning(s): |
Avoid freeze/thaw cycles |
| Scientific Category: |
Kinase(s) |
| Product Type: |
Receptor Tyrosine |
