BRK

Description: Human BRK, also known as PTK6 (GenBank Accession No. NM_005975), 2-451 (end), with N-terminal GST-tag, MW=80 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
Synonym(s): PTK6, FLJ42088
Specific Activity: 88 pmol/min/
Assay Conditions: Enzyme reaction was conducted in a buffer (25
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.1 mM EDTA, 0.1 mM EGTA, 0.25 mM DTT, 0.1 mM PMSF, and 25% glycerol.
Format: aqueous buffer solution
Storage / Stability: >6 months at -80°C
Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Mitchell, PJ. et al. Oncogene. 1994 Aug,9(8):2383-90. 2. Mitchell, PJ. et al. Oncogene. 1997 Sep 18,15(12):1497-502. Erratum in: Oncogene 1998 Jul 9,17(1):129.
Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase(s)
Product Type: Cytoplasmic Tyrosine