2-Methoxyestradiol (2-MeOE2)

Description: 2-Methoxyestradiol (2-MeOE2), an endogenous metabolite of 17β-estradiol (E2), is an inhibitor of microtubule assembly that inhibits the polymerization of tubulin and interferes with mitotic spindle dynamics leading to the blockage of mitosis of human
Synonym(s): 2-Methoxyestradiol; 2-MeOE2; 2-methoxy Estradiol
Solubility: Soluble in DMSO
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s): 1. Tsutsui, T., et al. Carcinogensis 2000; 21(4): 735-740. 2. Attalla, H., et al. Biochem. Biophys. Res. Commun. 1996; 228: 467-473.
Scientific Category: Inhibitors / Activators
Product Type: Apoptosis