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- CAS Registry #:362-07-2
- Formula:C19H26O3
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Description: |
2-Methoxyestradiol (2-MeOE2), an endogenous metabolite of 17β-estradiol (E2), is an inhibitor of microtubule assembly that inhibits the polymerization of tubulin and interferes with mitotic spindle dynamics leading to the blockage of mitosis of human |
Synonym(s): |
2-Methoxyestradiol; 2-MeOE2; 2-methoxy Estradiol |
Solubility: |
Soluble in DMSO |
Storage / Stability: |
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. |
Reference(s): |
1. Tsutsui, T., et al. Carcinogensis 2000; 21(4): 735-740.
2. Attalla, H., et al. Biochem. Biophys. Res. Commun. 1996; 228: 467-473. |
Scientific Category: |
Inhibitors / Activators |
Product Type: |
Apoptosis |