AICAR

Description:

AICAR, also known as acadesine, is an adenosine regulating agent and AMPK activator. AICAR was found to activate AMP-activated protein kinase (AMPK) in skeletal muscle, inhibit acetyl-CoA carboxylase, reduce malonyl-CoA, and increase fatty acid oxidation

Reference(s):

Merrill, G.F., et al. Am. J. Physiol. 273: E1107-E1112 (1997).

Synonym(s):

Acadesine, AIC -Riboside, 5-Aminoimidazole-4-carboxamide riboside

Purity:

≥99%

Solubility:

Soluble in DMSO at 40 mg/ml; soluble in ethanol at 2 mg/ml with warming; soluble in water at 20 mg/ml with warming

Format:

Tan powder

Storage / Stability:

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Scientific Category: Inhibitors / Activators
Product Type: Acetyltransferase