| Description: | The TEAD Reporter |
|---|---|
| Synonym(s): | Hippo, Hippo signalling pathway, Hippo signalling cascade, Salvador-Warts-Hippo signalling pathway, SWH signalling pathway |
| Supplied As: | Each vial contains ~1.5 X 10^6 cells in 1 ml of 10% DMSO. |
| Host Cell line: | MCF7 |
| Mycoplasma Testing: | The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma-Aldrich) to confirm the absence of Mycoplasma species. |
| Instructions for use: | See data sheet for detailed culturing and assay protocol. |
| Storage / Stability: | Immediately upon receipt, store in liquid nitrogen. |
| Application(s): | Monitor Hippo pathway activity. Screen for activators or inhibitors of the Hippo pathway. |
| Reference(s): | 1. Lamar JM et al. (2012) The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci U S A. 109(37):E2441-50. doi: 10.1073/pnas.1212021109. 2. Hata Y et al. (2013) Okadaic Acid: a tool to study the hippo pathway. Mar Drugs. 11(3):896-902. doi: 10.3390/md11030896. 3. Bao Y et al. (2011) A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription. J Biochem. 150(2):199-208. |
| Notes: | • Contact us for pricing • License Disclosure Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. Publications using this cell line should reference West Bioscience, Inc., San Diego. |
| Scientific Category: | Hippo Pathway TEAD Reporter - MCF7 Cell Line |
| Product Type: | |