| Description: | The HSP90α (C-Terminal) Inhibitor Screening Assay Kit is designed to measure the inhibition of HSP90α binding to its protein target PPID (also known as Cyclophilin D). With this kit, only three simple steps on a microtiter plate are required. |
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| UniProt | P07900 |
| Synonym(s): | HSP90alpha, Heat Shock Protein 90 alpha |
| Supplied As: | The assay kit comes in a convenient AlphaLISA |
| Contraindications: | Only limited amounts of DMSO (< 1%) can be included as it has been shown to disrupt HSP90?:PPID interaction. Green and blue dyes that absorb light in the AlphaScreen |
| Format: | |
| Storage / Stability: | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
| Application(s): | Useful for screening inhibitors of HSP90? and for HSP90? binding assays |
| Reference(s): | Allan, R.K. et al. J. Biol.Chem 2006. 281(11): 7161-71. |
| Notes: | AlphaScreen |
| Warning(s): | Avoid freeze/thaw cycles. |
| Scientific Category: | Heat Shock Proteins |
| Product Type: | Assay Kits |