| Description: | The Fluorogenic FAP Assay Kit is designed to measure FAP activity using purified FAP for screening and profiling applications. The key to the Fluorogenic FAP Assay Kit is the fluorogenic substrate. Using this kit, only one simple step on a microtiter |
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| UniProt | P48147 |
| Synonym(s): | Prolyl Oligopeptidase, POP, PREP, Prolyl Endopeptidase |
| Supplied As: | Supplied in a convenient 96-well format, with purified POP enzyme, substrate, and assay buffer for 100 enzymereactions. |
| Contraindications: | DMSO >1%, strong acids or bases, ionic detergents, high salt |
| Format: | |
| Storage / Stability: | At least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
| Application(s): | Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
| Reference(s): | 1. Myohanen T.T. et al., Neurochem. Res. 32 (8), 1365-1374 (2007). 2. Garcia-Horsman J.A. et al., Scand. J. Gastroenterol. 42 (5), 562-571 (2007). |
| Notes: | The AMC standard is included so the researcher can quatitatively determine the specific activity of the enzyme using the AMC standard as a measure of how much AMC substrate was cleaved to release free AMC. |
| Warning(s): | Avoid freeze/thaw cycles |
| Scientific Category: | FAP Assay Kit |
| Product Type: | |