- Species:Human
- Host Species:Sf9 insect cells
- MW:56 kDa
|
- Genbank #:NM_004964
- Tag(s):C-terminal FLAG-tag, C-terminal His-tag
- a.a:full length
|
| Description: |
Human HDAC1, GenBank Accession No. NM_004964, full length with C-terminal FLAG and C-terminal His-tag, MW= 56 kDa, expressed in baculovirus expression system. |
| UniProt |
Q13547 |
| Synonym(s): |
histone deacetylase 1, HDAC-1 |
| Specific Activity: |
≥460 pmol/min/ |
| Assay Conditions: |
25 mM Tris/HCl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2, and 0.1 mg/ml BSA, 20 |
| Formulation: |
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/ |
| Format: |
aqueous buffer solution |
| Storage / Stability: |
>6 months at -80°C. |
| Application(s): |
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Reference(s): |
1. Rikimaru,T. et al., Oncology 72 (1-2), 69-74 (2007).
2. Ishihama, K. et al., J Clin Pathol 60(11), 1205-10 (2007).
Application References
1. Sippl, W., et al., Methods and Principles in Med. Chem. 42:122 (2009).
2. Haggarty, S.J., et al. Small-Molecule Probes 54 |
| Warning(s): |
Avoid freeze/thaw cycles. |
| Scientific Category: |
Deacetylase(s) |
| Product Type: |
Enzymes |
