Frizzled-7, Fc Fusion

Description: Secreted frizzled receptor (FZD7)-Fc fusion protein and WNT receptor, also known as FZD7, GenBank Accession No. BC_015915, a.a. 33-185, expressed in a HEK293 cell expression system. MW = 43.3 kDa (monomer). This protein runs at a higher apparent M.W
UniProt O75084
Synonym(s): FZD7, Frizzled 7
Formulation: Sterile-filtered (0.2 µm) solution of 40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format: aqueous buffer solution
Storage / Stability: >6 months at
Application(s): Useful for binding studies, screening inhibitors, and selectivity profiling.
Reference(s): 1. Moffat LL., et al., Development. 2014 Feb;141(3):617-28. 2. Surana, R., et al., Biochim Biopys Acta. 2014 Jan;1845(1):53-65.
Warning(s): Avoid freeze/thaw cycles.
Scientific Category: Cell Surface Receptors
Product Type: GPCR