| Description: | The PD-1:PD-L1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-L1 by streptavidin-HRP. Only a few simple steps |
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| Supplied As: | Kit comes in a convenient 96-well format, withbiotin-labeled PD-L1, purified PD-1, streptavidin-labeled HRP, and assay buffer for 100binding reactions. |
| Contraindications: | DMSO >1%, strong acids or bases, ionic detergents, high salt. |
| Format: | |
| Storage / Stability: | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
| Application(s): | This kit is useful for screening for inhibitors of PD1 binding to PD-L1 |
| Reference(s): | 1. Lin, D., et al. Proc Natl Acad Sci U.S.A. 2008, 105: 3011-3016. 2. Keir, M.E. et al. Annu. Rev. Immunol. 2008, 26: 677-704. |
| Warning(s): | Avoid freeze/thaw cycles. |
| Scientific Category: | Cell Surface Receptors |
| Product Type: | Assay Kits |