| Description: | The CD28:B7-1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD28:B7-1 signaling. The key to this kit is the high sensitivity of detection of biotin-labeled B7-1 by streptavidin-HRP. Only a few simple ste |
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| UniProt | P10747 |
| Synonym(s): | CD80, B7.1 |
| Supplied As: | This kit comes in a convenient 96-well format, with biotin-labeled B7-1, purified CD28, streptavidin-labeled HRP, and assay buffer for 100 binding reactions. |
| Contraindications: | DMSO >1%, strong acids or bases, ionic detergents, high salt. |
| Format: | |
| Instructions for use: | See assay kit data sheet for detailed protocol |
| Storage / Stability: | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
| Application(s): | This kit is useful for screening for inhibitors of B7-1 binding to CD28. |
| Reference(s): | 1. Keir, M.E., et al. Immunol. Rev. 2005, 204: 128-143. 2. Haas, C., et al. Int. J. Cancer. 2006, 1;118: 658-667. |
| Warning(s): | Avoid freeze/thaw cycles. |
| Scientific Category: | Cell Surface Receptors |
| Product Type: | Assay Kits |