|
|
- CAS Registry #:328968-36-1
- Formula:C24H19N3O6
|
| Description: |
C646, a pyrazolone-containing small molecule, is a cell-permeable histone acetyltransferase (HAT) inhibitor that competitively and selectively inhibits the HAT activity of p300, a transcriptional co-activator involved in a variety of gene regulatory pathw |
| Synonym(s): |
4-[(4Z)-4-[[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid |
| Solubility: |
Soluble in DMSO |
| Storage / Stability: |
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. |
| Reference(s): |
Bowers EM, et al. Chem Biol. 2010 May 28;17(5):471-82. |
| Scientific Category: |
C646 |
| Product Type: |
|