- Species:Human
- Host Species:E. coli
- MW:35.1 kDa
|
- Genbank #:NM_001227
- Tag(s):C-terminal His-tag
- a.a:full length
|
| Description: |
Human Caspase-7 (full length) (GenBank Accession No. NM_001227) with C-terminal His-tag, MW= 35.1 kDa, expressed in an <i>E. coli</i> expression system. Active caspase 7 is a heterotetramer consisting of two copies each of ~20 kDa and ~11 kDa subunits. |
| UniProt |
P55210 |
| Synonym(s): |
Caspase-7, CASP7, Caspase 7, Mch3, ICE-LAP3 |
| Specific Activity: |
≥ 5337 pmol/min/ |
| Assay Conditions: |
Assayed using BPSs Homogeneous Caspase-7 Assay Kit, Cat. # 80701. 10 mM HEPES, pH 7.4, 10 mM EDTA, 0.05% Chaps, 5 mM DTT, and 10 |
| Formulation: |
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 155 mM imidazole, 20% glycerol and 3 mM DTT. |
| Format: |
aqueous buffer solution |
| Storage / Stability: |
>6 months at -80°C. |
| Application(s): |
Useful for the study of enzyme kinetics, screening inhibitors,and selectivity profiling. |
| Reference(s): |
Wang DH., et al., PLoS one,7(6):e39920. doi:10.1371/journal.0039920. (2012). |
| Warning(s): |
Avoid freeze/thaw cycles. |
| Scientific Category: |
Apoptosis |
| Product Type: |
Proteins |
