| Description: | The TNKS1 Histone Ribosylation Colorimetric Assay Kit is designed to measure Tankyrase 1 (TNKS1) activity for screening and profiling applications. TNKS1 catalyzes the NAD-dependent addition of poly(ADP-ribose) to the substrate proteins. The key to the T |
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| Synonym(s): | TNKS1, poly(ADP-ribose)polymerase 5a, poly(ADP-ribosyl)transferase 5a, PARP5A, TRF1-interacting ankyrin-related ADP-ribose polymerase 1, TANK1, tanykyrase-1 |
| Supplied As: | The TNKS1 assay kit comes in a convenient 96-well format, with purified TNKS1 enzyme, histone mixture, and PARP assay buffer for 100 enzyme reactions. |
| Format: | |
| Instructions for use: | See assay kit data sheet for detailed protocol |
| Storage / Stability: | Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
| Application(s): | Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
| Reference(s): | Brown, J.A., Marala, R.B. J. Pharmacol. Toxicol. Methods 2002 47:137-41. |
| Warning(s): | Avoid freeze/thaw cycles. |
| Scientific Category: | TNKS1 Histone Ribosylation Colorimetric Assay Kit |
| Product Type: | |