- Species:Human
- Host Species:HEK293
- MW:38.4 kDa
|
- Genbank #:NP_542970
- Tag(s):C-terminal His-tag
- a.a:27-370
|
| Description: |
Signal regulatory protein-alpha (SIRP-α), also known as Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NP_542970, a.a. 27-370, with C-terminal His-tag, MW 38.4 kDa*, expressed in a HEK293 expression system. This protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in apparent higher molecular weight. |
| UniProt |
P78324 |
| Synonym(s): |
Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1 |
| Formulation: |
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol |
| Format: |
Aqueous buffer solution |
| Storage / Stability: |
>6 months at -80 |
| Application(s): |
Useful for studying protein binding and screening small molecules. |
| Reference(s): |
1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77
2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63 |
| Warning(s): |
Avoid freeze/thaw cycles. |
| Scientific Category: |
SIRP-α (CD172a), His-tag |
| Product Type: |
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