| Description: | The HSP90β Assay Kit is designed for identification of HSP90β inhibitors using fluorescence polarization. The assay is based on the competition of fluorescently labeled geldanamycin for binding to purified recombinant HSP90β. The key to the HSP90β Assay K |
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| UniProt | P08238 |
| Synonym(s): | HSP90b, Heat Shock Protein 90b, HSP90beta, HSP90β |
| Supplied As: | The HSP90? inhibitor screening assay kit comes in a convenient 384-well format, with purified HSP90? enzyme, fluorescently labeled geldanamycin and HSP90 assay buffer for 384 enzyme reactions. |
| Contraindications: | DMSO >1%, strong acids or bases, ionic detergents, high salt |
| Format: | |
| Instructions for use: | See data sheet for detailed protocol. |
| Storage / Stability: | Stable for at least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. |
| Application(s): | Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications. |
| Reference(s): | 1. Kim, J., et al. J Biomol Screening 2004, 9(5): 375-381. 2. Howes, R., et al. Anal Biochem 2006, 350:202-213. |
| Warning(s): | Avoid freeze/thaw cycles |
| Scientific Category: | HSP90β Assay Kit |
| Product Type: | |